For a comprehensive list of Jacob Raber's publications, click here
2024
2023
Weiss, J. B., & Raber, J. (2023). Inhibition of Anaplastic Lymphoma Kinase (Alk) as Therapeutic Target to Improve Brain Function in Neurofibromatosis Type 1 (Nf1). Cancers, 15(18), 4579. MDPI AG. Retrieved from http://dx.doi.org/10.3390/cancers15184579
Gaston, G., Babcock, S., Ryals, R. et al. A G1528C Hadha knock-in mouse model recapitulates aspects of human clinical phenotypes for long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency. Commun Biol 6, 890 (2023). https://doi.org/10.1038/s42003-023-05268-1
Merrill, N. J., Davidson, W. S., He, Y., Díaz Ludovico, I., Sarkar, S., Berger, M. R., McDermott, J. E., Van Eldik, L. J., Wilcock, D. M., Monroe, M. E., Kyle, J. E., Bruce, K. D., Heinecke, J. W., Vaisar, T., Raber, J., Quinn, J. F., & Melchior, J. T. (2023). Human cerebrospinal fluid contains diverse lipoprotein subspecies enriched in proteins implicated in central nervous system health. Science advances, 9(35), eadi5571. https://doi.org/10.1126/sciadv.adi5571
Chaklai, A., Canaday, P., O'Niel, A., Cucinotta, F. A., Sloop, A., Gladstone, D., Pogue, B., Zhang, R., Sunnerberg, J., Kheirollah, A., Thomas, C. R., Jr, Hoopes, P. J., & Raber, J. (2023). Effects of UHDR and Conventional Irradiation on Behavioral and Cognitive Performance and the Percentage of Ly6G+ CD45+ Cells in the Hippocampus. International journal of molecular sciences, 24(15), 12497. https://doi.org/10.3390/ijms241512497
Matei, B., Winters-Stone, K. M., & Raber, J. (2023). Examining the Mechanisms behind Exercise’s Multifaceted Impacts on Body, Cognition, and the Gut Microbiome in Cancer Survivors: Exploring the Links to Oxidative Stress and Inflammation. Antioxidants, 12(7), 1423. MDPI AG. Retrieved from http://dx.doi.org/10.3390/antiox12071423
Impey S, Pelz C, Riparip L-K, Tafessu A, Fareh F, Zuloaga DG, Marzulla T, Stewart B, Rosi S, Turker MS and Raber J (2023) Postsynaptic density radiation signature following space irradiation. Front. Physiol. 14:1215535. doi: 10.3389/fphys.2023.1215535
Raber J and Silbert LC (2023) Role of white matter hyperintensity in effects of apolipoprotein E on cognitive injury. Front. Hum. Neurosci. 17:1176690. doi: 10.3389/fnhum.2023.1176690
Kessler, K., Giannisis, A., Bial, G. et al. Behavioral and cognitive performance of humanized APOEε3/ε3 liver mice in relation to plasma apolipoprotein E levels. Sci Rep 13, 1728 (2023). https://doi.org/10.1038/s41598-023-28165-3
Boutros, S.W., Zimmerman, B., Nagy, S.C. et al. Age, sex, and apolipoprotein E isoform alter contextual fear learning, neuronal activation, and baseline DNA damage in the hippocampus. Mol Psychiatry (2023). https://doi.org/10.1038/s41380-023-01966-8
Erickson, M. A., Logsdon, A. F., Rhea, E. M., Hansen, K. M., Holden, S. J., Banks, W. A., Smith, J. L., German, C., Farr, S. A., Morley, J. E., Weaver, R. R., Hirsch, A. J., Kovac, A., Kontsekova, E., Baumann, K. K., Omer, M. A., & Raber, J. (2023). Blood-brain barrier penetration of non-replicating SARS-CoV-2 and S1 variants of concern induce neuroinflammation which is accentuated in a mouse model of Alzheimer's disease. Brain, behavior, and immunity, 109, 251–268. Advance online publication. https://doi.org/10.1016/j.bbi.2023.01.010
Raber, J.; Rhea, E.M.; Banks, W.A. The Effects of Viruses on Insulin Sensitivity and Blood–Brain Barrier Function. Int. J. Mol. Sci. 2023, 24, 2377. https://doi.org/10.3390/ijms24032377
2022
Kundu, P., Holden, S., Paraiso, I. L., Sudhakar, R., McQuesten, C., Choi, J., Miranda, C. L., Maier, C. S., Bobe, G., Stevens, J. F., & Raber, J. (2022). ApoE isoform-dependent effects of xanthohumol on high fat diet-induced cognitive impairments and hippocampal metabolic pathways. Frontiers in Pharmacology, 13. https://doi.org/10.3389/fphar.2022.954980
Bah, T. M., Allen, E. M., Garcia-Jaramillo, M., Perez, R., Zarnegarnia, Y., Davis, C. M., Bloom, M. B., Magana, A. A., Choi, J., Bobe, G., Pike, M. M., Raber, J., Maier, C. S., & Alkayed, N. J. (2022). GPR39 deficiency impairs memory and alters oxylipins and inflammatory cytokines without affecting cerebral blood flow in a high-fat diet mouse model of cognitive impairment. Frontiers in Cellular Neuroscience, 16. https://doi.org/10.3389/fncel.2022.893030
van Ginkel, W. G., Winn, S. R., Dudley, S., Krenik, D., Perez, R., Rimann, N., Thöny, B., Raber, J., & Harding, C. O. (2022). Biochemical and behavioural profile of NTBC treated tyrosinemie type 1 mice. Molecular Genetics and Metabolism, 137(1-2), 9–17. https://doi.org/10.1016/j.ymgme.2022.07.001
Weber Boutros, S., Unni, V. K., & Raber, J. (2022). An adaptive role for DNA double-strand breaks in hippocampus-dependent learning and memory. International Journal of Molecular Sciences, 23(15), 8352. https://doi.org/10.3390/ijms23158352
Younger, S., Boutros, S., Cargnin, F., Jeon, S., Lee, J. W., Lee, S.-K., & Raber, J. (2022). Behavioral phenotypes of Foxg1 heterozygous mice. Frontiers in Pharmacology, 13. https://doi.org/10.3389/fphar.2022.927296
Rhea, E. M., Banks, W. A., & Raber, J. (2022). Insulin resistance in peripheral tissues and The brain: A tale of two sites. Biomedicines, 10(7), 1582. https://doi.org/10.3390/biomedicines10071582
Kundu, P., Zimmerman, B., Quinn, J.F., Kaye, F., Mattek, N., Westaway, S.K., Raber, J. (Febuary 2022) Serum Levels of a-Klotho are Correlated with Cerebrospinal Fluid Levels and Predict Measures of Cognitive Function. Journal of Alzheimer’s Disease. https://doi.org/10.3233/JAD-215719
Holden, S., Kundu, P., Torres, E. RS, Sudhakar, R., Krenik, D., Grygoryev, D., Turker, M. S., Raber, J. (March 2022) Apolipoprotein E Isoform-Dependent Effects on Human Amyloid Precursor Protein/Aβ-Induced Behavioral Alterations and Cognitive Impairments and Insoluble Cortical Aβ42 Levels. Frontiers. https://doi.org/10.3389/fnagi.2022.767558
Kundu, P., Zimmerman, B., Quinn, J. F., Kaye, J., Mattek, N., Westaway S. K., Raber, J. (February 2022) Serum Levels of α-Klotho Are Correlated with Cerebrospinal Fluid Levels and Predict Measures of Cognitive Function. Journal of Alzheimer’s Disease. 10.3233/JAD-215719
Kundu, P., Stagaman, K., Kasschau, K., Holden, S., Shulzhenko, N., Sharpton, T. J., & Raber, J. (2022). Fecal Implants From AppNL–G–F and AppNL–G–F/E4 Donor Mice Sufficient to Induce Behavioral Phenotypes in Germ-Free Mice. Frontiers. https://doi.org/10.3389/fnbeh.2022.791128
Boutros, S. W., Krenik, D., Holden, S., Unni, V. K., $ Raber, J. (January 2022). Common cancer treatments targeting DNA double strand breaks affect long-term memory and relate to immediate early gene expression in a sex-dependent manner. Oncotarget. https://doi.org/10.18632/oncotarget.28180
2021
Boutros, S. W., Zimmerman, B., Nagy, S. C., Lee, J. S., Perez, R., & Raber, J. (1AD, January 1). Amifostine (WR-2721) mitigates cognitive injury induced by heavy ion radiation in male mice and alters behavior and brain connectivity. Frontiers. Retrieved November 18, 2021, from https://www.frontiersin.org/articles/10.3389/fphys.2021.770502/full?&utm_source=Email_to_authors_&utm_medium=Email&utm_content=T1_11.5e1_author&utm_campaign=Email_publication&field=&journalName=Frontiers_in_Physiology&id=770502.
Kundu, P., Zimmerman, B., Perez, R. et al. Apolipoprotein E levels in the amygdala and prefrontal cortex predict relative regional brain volumes in irradiated Rhesus macaques. Sci Rep 11, 22130 (2021). https://doi.org/10.1038/s41598-021-01480-3
Minnier, J., Emmett, M.R., Perez, R. et al. Associations between lipids in selected brain regions, plasma miRNA, and behavioral and cognitive measures following 28Si ion irradiation. Sci Rep 11, 14899 (2021). https://doi.org/10.1038/s41598-021-93869-3
Holden, S., Perez, R., Hall, R., Fallgren, C. M., Ponnaiya, B., Garty, G., Brenner, D. J., Weil, M. M., & Raber, J. (2021). Effects of Acute and Chronic Exposure to a Mixed Field of Neutrons and Photons and Single or Fractionated Simulated Galactic Cosmic Ray Exposure on Behavioral and Cognitive Performance in Mice. Radiation Research, 196(1). https://doi.org/10.1667/rade-20-00228.1
Alpa Trivedi, Kayleen G. Tercovich, Amy Jo Casbon, Jacob Raber, Clifford Lowell, Linda J. Noble-Haeusslein. (2021). Neutrophil-specific deletion of Syk results in recruitment-independent stabilization of the barrier and a long-term improvement in cognitive function after traumatic injury to the developing brain. Neurobiology of Disease, Volume 157, 2021, 105430, ISSN 0969-9961, https://doi.org/10.1016/j.nbd.2021.105430.
Raber, J., Perez, R., Torres, E. R., Krenik, D., Boutros, S., Patel, E., Chlebowski, A. C., Torres, E. R., Perveen, Z., Penn, A., Paulsen, D. B., Bartlett, M. G., Jia, E., Holden, S., Hall, R., Morré, J., Wong, C., Ho, E., Choi, J., … Kisby, G. (2021). Effects of Chronic Secondhand Smoke (SHS) Exposure on Cognitive Performance and Metabolic Pathways in the Hippocampus of Wild-Type and Human Tau Mice. Environmental Health Perspectives, 129(5), 057009. https://doi.org/10.1289/ehp8428
Kundu, P., Torres, E.R.S., Stagaman, K. et al.Integrated analysis of behavioral, epigenetic, and gut microbiome analyses in AppNL-G-F, AppNL-F, and wild type mice. Sci Rep 11, 4678 (2021). https://doi.org/10.1038/s41598-021-83851-4
Weston LJ, Stackhouse TL, Spinelli KJ, Boutros SW, Rose EP, Osterberg VR, Luk KC, Raber J, Weissman TA, Unni VK. Genetic deletion of Polo-like kinase 2 reduces alpha-synuclein serine-129 phosphorylation in presynaptic terminals but not Lewy bodies. J Biol Chem. 2021 Jan 8:100273. doi: 10.1016/j.jbc.2021.100273. Epub ahead of print. PMID: 33428941.
2020
Rhea EM, Raber J, Banks WA. ApoE and cerebral insulin: Trafficking, receptors, and resistance. Neurobiol Dis. 2020 Apr;137:104755. doi: 10.1016/j.nbd.2020.104755. Epub 2020 Jan 21. PMID: 31978603; PMCID: PMC7050417.
Rhea EM, Logsdon AF, Hansen KM, Williams LM, Reed MJ, Baumann KK, Holden SJ, Raber J, Banks WA, Erickson MA. The S1 protein of SARS-CoV-2 crosses the blood-brain barrier in mice. Nat Neurosci. 2020 Dec 16. doi: 10.1038/s41593-020-00771-8. Epub ahead of print. PMID: 33328624.
Stefanova E, Dubljević O, Herbert C, Fairfield B, Schroeter ML, Stern ER, Urben S, Derntl B, Wiebking C, Brown C, Drach-Zahavy A, Kathrin Loeffler LA, Albrecht F, Palumbo R, Boutros SW, Raber J, Lowe L. Anticipatory feelings: Neural correlates and linguistic markers. Neurosci Biobehav Rev. 2020 Jun;113:308-324. doi: 10.1016/j.neubiorev.2020.02.015. Epub 2020 Feb 13. PMID: 32061891.
Burfeind KG, Zhu X, Norgard MA, Levasseur PR, Huisman C, Buenafe AC, Olson B, Michaelis KA, Torres ER, Jeng S, McWeeney S, Raber J, Marks DL. Circulating myeloid cells invade the central nervous system to mediate cachexia during pancreatic cancer. Elife. 2020 May 11;9:e54095. doi: 10.7554/eLife.54095. PMID: 32391790; PMCID: PMC7253193.
Rhea EM, Torres ERS, Raber J, Banks WA. Insulin BBB pharmacokinetics in young apoE male and female transgenic mice. PLoS One. 2020 Jan 31;15(1):e0228455. doi: 10.1371/journal.pone.0228455. PMID: 32004344; PMCID: PMC6993976.
Torres ERS, Weber Boutros S, Meshul CK, Raber J. ApoE isoform-specific differences in behavior and cognition associated with subchronic MPTP exposure. Learn Mem. 2020 Aug 17;27(9):372-379. doi: 10.1101/lm.052126.120. PMID: 32817303; PMCID: PMC7433653.
Paraiso IL, Revel JS, Choi J, Miranda CL, Lak P, Kioussi C, Bobe G, Gombart AF, Raber J, Maier CS, Stevens JF. Targeting the Liver-Brain Axis with Hop-Derived Flavonoids Improves Lipid Metabolism and Cognitive Performance in Mice. Mol Nutr Food Res. 2020 Aug;64(15):e2000341. doi: 10.1002/mnfr.202000341. Epub 2020 Jul 6. PMID: 32627931.
Perez RE, Younger S, Bertheau E, Fallgren CM, Weil MM, Raber J. Effects of chronic exposure to a mixed field of neutrons and photons on behavioral and cognitive performance in mice. Behav Brain Res. 2020 Feb 3;379:112377. doi: 10.1016/j.bbr.2019.112377. Epub 2019 Nov 22. PMID: 31765722.
Raber J, Fuentes Anaya A, Torres ERS, Lee J, Boutros S, Grygoryev D, Hammer A, Kasschau KD, Sharpton TJ, Turker MS, Kronenberg A. Effects of Six Sequential Charged Particle Beams on Behavioral and Cognitive Performance in B6D2F1 Female and Male Mice. Front Physiol. 2020 Aug 28;11:959. doi: 10.3389/fphys.2020.00959. PMID: 32982769; PMCID: PMC7485338.
Zimmerman B, Kundu P, Liu Z, Urbanski HF, Kroenke CD, Kohama SG, Bethea CL, Raber J. Longitudinal Effects of Immediate and Delayed Estradiol on Cognitive Performance in a Spatial Maze and Hippocampal Volume in Menopausal Macaques Under an Obesogenic Diet. Front Neurol. 2020 Jun 24;11:539. doi: 10.3389/fneur.2020.00539. PMID: 32670182; PMCID: PMC7326936.
2019
Schaser AJ, Osterberg VR, Dent SE, Stackhouse TL, Wakeham CM, Boutros SW, Weston LJ, Owen N, Weissman TA, Luna E, Raber J, Luk KC, McCullough AK, Woltjer RL, Unni VK. Alpha-synuclein is a DNA binding protein that modulates DNA repair with implications for Lewy body disorders. Sci Rep. 2019 Jul 29;9(1):10919. doi: 10.1038/s41598-019-47227-z. PMID: 31358782; PMCID: PMC6662836.
Raber J, Arzy S, Bertolus JB, Depue B, Haas HE, Hofmann SG, Kangas M, Kensinger E, Lowry CA, Marusak HA, Minnier J, Mouly AM, Mühlberger A, Norrholm SD, Peltonen K, Pinna G, Rabinak C, Shiban Y, Soreq H, van der Kooij MA, Lowe L, Weingast LT, Yamashita P, Boutros SW. Current understanding of fear learning and memory in humans and animal models and the value of a linguistic approach for analyzing fear learning and memory in humans. Neurosci Biobehav Rev. 2019 Oct;105:136-177. doi: 10.1016/j.neubiorev.2019.03.015. Epub 2019 Apr 7. PMID: 30970272.
Taqui S, Ferencik M, Davidson BP, Belcik JT, Moccetti F, Layoun M, Raber J, Turker M, Tavori H, Fazio S, Lindner JR. Coronary Microvascular Dysfunction by Myocardial Contrast Echocardiography in Nonelderly Patients Referred for Computed Tomographic Coronary Angiography. J Am Soc Echocardiogr. 2019 Jul;32(7):817-825. doi: 10.1016/j.echo.2019.03.001. Epub 2019 May 15. PMID: 31103385; PMCID: PMC6527356.
Perez RE, Younger S, Bertheau E, Fallgren CM, Weil MM, Raber J. Effects of chronic exposure to a mixed field of neutrons and photons on behavioral and cognitive performance in mice. Behav Brain Res. 2020 Feb 3;379:112377. doi: 10.1016/j.bbr.2019.112377. Epub 2019 Nov 22. PMID: 31765722.
Raber J, Yamazaki J, Torres ERS, Kirchoff N, Stagaman K, Sharpton T, Turker MS, Kronenberg A. Combined Effects of Three High-Energy Charged Particle Beams Important for Space Flight on Brain, Behavioral and Cognitive Endpoints in B6D2F1 Female and Male Mice. Front Physiol. 2019 Mar 12;10:179. doi: 10.3389/fphys.2019.00179. PMID: 30914962; PMCID: PMC6422905.
Torres ERS, Hall R, Bobe G, Choi J, Impey S, Pelz C, Lindner JR, Stevens JF, Raber J. Integrated Metabolomics-DNA Methylation Analysis Reveals Significant Long-Term Tissue-Dependent Directional Alterations in Aminoacyl-tRNA Biosynthesis in the Left Ventricle of the Heart and Hippocampus Following Proton Irradiation. Front Mol Biosci. 2019 Sep 10;6:77. doi: 10.3389/fmolb.2019.00077. PMID: 31552266; PMCID: PMC6746933.
Johnson LA, Torres ER, Weber Boutros S, Patel E, Akinyeke T, Alkayed NJ, Raber J. Apolipoprotein E4 mediates insulin resistance-associated cerebrovascular dysfunction and the post-prandial response. J Cereb Blood Flow Metab. 2019 May;39(5):770-781. doi: 10.1177/0271678X17746186. Epub 2017 Dec 7. PMID: 29215310; PMCID: PMC6498752.
2018
Lee B, Kim J, An T, Kim S, Patel EM, Raber J, Lee SK, Lee S, Lee JW. Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons. Nat Commun. 2018 May 23;9(1):2026. doi: 10.1038/s41467-018-04377-4. PMID: 29795232; PMCID: PMC5966420.
Iancu OD, Boutros SW, Olsen RHJ, Davis MJ, Stewart B, Eiwaz M, Marzulla T, Belknap J, Fallgren CM, Edmondson EF, Weil MM, Raber J. Space Radiation Alters Genotype-Phenotype Correlations in Fear Learning and Memory Tests. Front Genet. 2018 Oct 9;9:404. doi: 10.3389/fgene.2018.00404. PMID: 30356920; PMCID: PMC6190902.
Miranda CL, Johnson LA, de Montgolfier O, Elias VD, Ullrich LS, Hay JJ, Paraiso IL, Choi J, Reed RL, Revel JS, Kioussi C, Bobe G, Iwaniec UT, Turner RT, Katzenellenbogen BS, Katzenellenbogen JA, Blakemore PR, Gombart AF, Maier CS, Raber J, Stevens JF. Non-estrogenic Xanthohumol Derivatives Mitigate Insulin Resistance and Cognitive Impairment in High-Fat Diet-induced Obese Mice. Sci Rep. 2018 Jan 12;8(1):613. doi: 10.1038/s41598-017-18992-6. PMID: 29330372; PMCID: PMC5766630.
Raber J, Torres ERS, Akinyeke T, Lee J, Weber Boutros SJ, Turker MS, Kronenberg A. Detrimental Effects of Helium Ion Irradiation on Cognitive Performance and Cortical Levels of MAP-2 in B6D2F1 Mice. Int J Mol Sci. 2018 Apr 20;19(4):1247. doi: 10.3390/ijms19041247. PMID: 29677125; PMCID: PMC5979430.
Bading-Taika B, Akinyeke T, Magana AA, Choi J, Ouanesisouk M, Torres ERS, Lione LA, Maier CS, Bobe G, Raber J, Miranda CL, Stevens JF. Phytochemical characterization of Tabernanthe iboga root bark and its effects on dysfunctional metabolism and cognitive performance in high-fat-fed C57BL/6J mice. J Food Bioact. 2018 Sep;3:111-123. doi: 10.31665/JFB.2018.3154. Epub 2018 Sep 30. PMID: 30582133; PMCID: PMC6301038.
Torres ERS, Akinyeke T, Stagaman K, Duvoisin RM, Meshul CK, Sharpton TJ, Raber J. Effects of Sub-Chronic MPTP Exposure on Behavioral and Cognitive Performance and the Microbiome of Wild-Type and mGlu8 Knockout Female and Male Mice. Front Behav Neurosci. 2018 Jul 18;12:140. doi: 10.3389/fnbeh.2018.00140. PMID: 30072879; PMCID: PMC6058038.
Winn SR, Scherer T, Thöny B, Ying M, Martinez A, Weber S, Raber J, Harding CO. Blood phenylalanine reduction corrects CNS dopamine and serotonin deficiencies and partially improves behavioral performance in adult phenylketonuric mice. Mol Genet Metab. 2018 Jan;123(1):6-20. doi: 10.1016/j.ymgme.2017.10.009. Epub 2017 Oct 19. PMID: 29331172; PMCID: PMC5786171.
2017
McGinnis GJ, Raber J. CNS side effects of immune checkpoint inhibitors: preclinical models, genetics and multimodality therapy. Immunotherapy. 2017 September 9(11):929-941. doi: 10.2217/imt-2017-0056.
Villasana LE, Akinyeke T, Weber S, Raber J. Paradoxical effects of 137Cs irradiation on pharmacological stimulation of reactive oxygen species in hippocampal slices from apoE2 and apoE4 mice. Oncotarget. 2017 Sep 1;8(44):76587-76605. doi: 10.18632/oncotarget.20603.
Impey S, Jopson T, Pelz C, Tafessu A, Fareh F, Zuloaga D, Marzulla T, Riparip LK, Stewart B, Rosi S, Turker MS, Raber J. Bi-directional and shared epigenomic signatures following proton and 56Fe irradiation. Scientific Reports. 2017 Aug 31;7(1):10227. doi: 10.1038/s41598-017-09191-4.
Weiss JB, Weber S, Marzulla T, Raber J. Pharmacological inhibition of Anaplastic Lymphoma Kinase rescues spatial memory impairments in Neurofibromatosis 1 mutant mice. Behav Brain Res. 2017 Aug 14;332:337-342. doi: 10.1016/j.bbr.2017.06.024.
Johnson LA, Torres ER, Impey S, Stevens JF, Raber J. Apolipoprotein E4 and Insulin Resistance Interact to Impair Cognition and Alter the Epigenome and Metabolome. Scientific Reports. 2017 Mar 8;7:43701. doi: 10.1038/srep43701.
Weiss JB, Weber SJ, Torres ERS, Marzulla T, Raber J. Genetic inhibition of Anaplastic Lymphoma Kinase rescues cognitive impairments in Neurofibromatosis 1 mutant mice. Behav Brain Res. 2017 Mar 15;321:148-156. doi: 10.1016/j.bbr.2017.01.003.
Raber J, Davis MJ, Pfankuch T, Rosenthal R, Doctrow SR, Moulder JE. Mitigating effect of EUK-207 on radiation-induced cognitive impairments. Behav Brain Res. 2017 Mar 1;320:457-463. doi: 10.1016/j.bbr.2016.10.038.
Olsen RH, Weber SJ, Akinyeke T, Raber J. Enhanced cued fear memory following post-training whole body irradiation of 3-month-old mice. Behav Brain Res. 2017 Feb 15;319:181-187. doi: 10.1016/j.bbr.2016.11.031.
McGinnis GJ, Friedman D, Young KH, Torres ER, Thomas CR Jr, Gough MJ, Raber J. Neuroinflammatory and cognitive consequences of combined radiation and immunotherapy in a novel preclinical model. Oncotarget. 2017 Feb 7;8(6):9155-9173. doi: 10.18632/oncotarget.13551.
Johnson LA, Torres ER, Weber Boutros S, Patel E, Akinyeke T, Alkayed NJ, Raber J. Apolipoprotein E4 mediates insulin resistance-associated cerebrovascular dysfunction and the post-prandial response. J Cereb Blood Flow Metab. 2017 Jan 1:271678X17746186. doi: 10.1177/0271678X17746186.
2016
Impey S, Jopson T, Pelz C, Tafessu A, Fareh F, Zuloaga D, Marzulla T, Riparip LK, Stewart B, Rosi S, Turker MS, Raber J. Short- and long-term effects of 56Fe irradiation on cognition and hippocampal DNA methylation and gene expression. BMC Genomics. 2016 Oct 24;17(1):825.
Villasana LE, Weber S, Akinyeke T, Raber J. Genotype differences in anxiety and fear learning and memory of WT and ApoE4 mice associated with enhanced generation of hippocampal reactive oxygen species. J Neurochem. 2016 Sep;138(6):896-908. doi: 10.1111/jnc.13737.
Raber J, Weber SJ, Kronenberg A, Turker MS. Sex- and dose-dependent effects of calcium ion irradiation on behavioral performance of B6D2F1 mice during contextual fear conditioning training. Life Sci Space Res (Amst). 2016 Jun;9:56-61. doi: 10.1016/j.lssr.2016.03.002.
Zuloaga DG, Wang J, Weber S, Mark GP, Murphy SJ, Raber J. Chronic methamphetamine exposure prior to middle cerebral artery occlusion increases infarct volume and worsens cognitive injury in Male mice. Metab Brain Dis. 2016 Aug;31(4):975-81. doi: 10.1007/s11011-016-9808-z.
Raber J, Allen AR, Weber S, Chakraborti A, Sharma S, Fike JR. Effect of behavioral testing on spine density of basal dendrites in the CA1 region of the hippocampus modulated by (56)Fe irradiation. Behav Brain Res. 2016 Apr 1;302:263-8. doi: 10.1016/j.bbr.2016.01.035.
Impey S, Pelz C, Tafessu A, Marzulla T, Turker MS, Raber J. Proton irradiation induces persistent and tissue-specific DNA methylation changes in the left ventricle and hippocampus. BMC Genomics. 2016 Mar 31;17:273. doi: 10.1186/s12864-016-2581-x.
Zuloaga DG, Lahvis GP, Mills B, Pearce HL, Turner J, Raber J. Fetal domoic acid exposure affects lateral amygdala neurons, diminishes social investigation and alters sensory-motor gating. Neurotoxicology. 2016 Mar;53:132-140. doi: 10.1016/j.neuro.2016.01.007.
Akinyeke T, Weber SJ, Davenport AT, Baker EJ, Daunais JB, Raber J. Effects of alcohol on c-Myc protein in the brain. Behav Brain Res. 2017 Mar 1;320:356-364. doi: 10.1016/j.bbr.2016.11.009.
Zuloaga DG, Johnson LA, Weber S, Raber J. Immediate and lasting effects of chronic daily methamphetamine exposure on activation of cells in hypothalamic-pituitary-adrenal axis-associated brain regions. Psychopharmacology (Berl). 2016 Feb;233(3):381-92. doi: 10.1007/s00213-015-4114-8.
Kugelman T, Zuloaga DG, Weber S, Raber J. Post-training gamma irradiation-enhanced contextual fear memory associated with reduced neuronal activation of the infralimbic cortex. Behav Brain Res. 2016 Feb 1;298(Pt B):1-11. doi: 10.1016/j.bbr.2015.10.050.
Raber J, Allen AR, Sharma S, Allen B, Rosi S, Olsen RH, Davis MJ, Eiwaz M, Fike JR, Nelson GA. Effects of Proton and Combined Proton and (56)Fe Radiation on the Hippocampus. Radiat Res. 2016 Jan;185(1):20-30. doi: 10.1667/RR14222.1.
Johnson LA, Zuloaga KL, Kugelman TL, Mader KS, Morré JT, Zuloaga DG, Weber S, Marzulla T, Mulford A, Button D, Lindner JR, Alkayed NJ, Stevens JF, Raber J. Amelioration of Metabolic Syndrome-Associated Cognitive Impairments in Mice via a Reduction in Dietary Fat Content or Infusion of Non-Diabetic Plasma. EBioMedicine. 2015 Dec 12;3:26-42. doi: 10.1016/j.ebiom.2015.12.008. eCollection 2016 Jan.
2015
Raber J, Marzulla T, Kronenberg A, Turker MS. (16)Oxygen irradiation enhances cued fear memory in B6D2F1 mice. Life Sci Space Res (Amst). 2015 Nov;7:61-5. doi: 10.1016/j.lssr.2015.10.004.
Zuloaga DG, Iancu OD, Weber S, Etzel D, Marzulla T, Stewart B, Allen CN, Raber J. Enhanced functional connectivity involving the ventromedial hypothalamus following methamphetamine exposure. Front Neurosci. 2015 Sep 23;9:326. doi: 10.3389/fnins.2015.00326.
Johnson LA, Zuloaga DG, Bidiman E, Marzulla T, Weber S, Wahbeh H, Raber J. ApoE2 Exaggerates PTSD-Related Behavioral, Cognitive, and Neuroendocrine Alterations. Neuropsychopharmacology. 2015 Sep;40(10):2443-53. doi: 10.1038/npp.2015.95.
Raber J, Marzulla T, Stewart B, Kronenberg A, Turker MS. 28Silicon Irradiation Impairs Contextual Fear Memory in B6D2F1 Mice. Radiat Res. 2015 Jun;183(6):708-12.
Zuloaga DG, Jacobskind JS, Raber J. Methamphetamine and the hypothalamic-pituitary-adrenal axis. Front Neurosci. 2015 May 27;9:178. doi: 10.3389/fnins.2015.00178.
Raber J. Novel images and novel locations of familiar images as sensitive translational cognitive tests in humans. Behav Brain Res. 2015 May 15;285:53-9. doi: 10.1016/j.bbr.2015.01.046.
Raber J, Duvoisin RM. Novel metabotropic glutamate receptor 4 and glutamate receptor 8 therapeutics for the treatment of anxiety. Expert Opin Investig Drugs. 2015 Apr;24(4):519-28. doi: 10.1517/13543784.2014.986264.